Longevity AI Launches Promicsedge Integration, Bringing 200 Million Genetic Variants Into the Complete Patient Picture

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Every patient’s starting point was written before they ever walked into your clinic.

Their DNA is not the whole story. But it is the first layer of it, and it can shape everything that follows.

Today, Longevity AI launched a live integration with PromicsEdge, one of the world’s most comprehensive precision-health platforms.

PromicsEdge analyzes 200 million SNPs and supports more than 1,500 health reports, drawing on over 100,000 scientific references. Its algorithms have been validated using public datasets representing more than two million genome samples, with ancestry-adjusted polygenic risk scoring designed to make genetic risk estimates more relevant across diverse populations.

Now, that depth of genetic intelligence can flow directly into Longevity AI.

Clinics can order an at-home DNA test for a patient through their practice. The patient completes it at home, and when the results are ready, they appear inside Longevity AI with no reports to download, upload, or manually reconcile.

Florence, Longevity AI’s clinical companion, reads those genetic findings alongside the patient’s labs, wearable signals, goals, and complete clinical history. She interprets each signal against the patient’s own baseline and trajectory, then drafts a prioritized, personalized care plan for the clinician to review, edit, and approve.

Genomic depth meets longitudinal clinical intelligence

PromicsEdge brings extraordinary depth to the patient’s genetic starting point:

• 200 million SNPs analyzed
• 1,500+ health reports
• 4,000+ lab biomarkers supported
• 20,000+ recommendations in its database
• 100,000+ scientific references across its reports
• 2 million+ genome samples represented in public validation datasets
• Ancestry-adjusted polygenic risk scoring
• Published, peer-reviewed algorithm validation

Longevity AI adds the patient’s story over time.

Florence brings the PromicsEdge results together with longitudinal biomarkers, medical history, medications, symptoms, lifestyle, and continuous signals from wearables. Longevity AI’s clinical models, built using more than 1.6 million longitudinal, de-identified patient records, help her recognize meaningful patterns across cardiovascular, metabolic, cognitive, immune, and other systems.

PromicsEdge helps reveal what a patient may be predisposed to. Longevity AI shows what is happening now, how it is changing, and what the clinician may want to do next.

A genetic cardiovascular risk can be considered alongside the patient’s current lipid profile and trajectory. A pharmacogenomic finding can be reviewed in the context of medications and clinical history. Nutrition, exercise, sleep, supplements, and follow-up testing can be prioritized around the signals that matter most for that individual.

Instead of another standalone report, the clinician gets one continuously updated patient picture.

“Personalized medicine has too often meant giving clinicians more data and leaving them to connect it by hand,” said Guy Leitersdorf, Founder and CEO of Longevity AI. “PromicsEdge can surface signals across 200 million genetic variants. Florence can read those findings against years of labs, wearables, clinical history, and goals. Together, they give the doctor a clear, patient-specific starting point for care.”

For clinics, the workflow stays simple: order the test, let the patient complete it at home, and receive the results directly inside Longevity AI. Florence performs the synthesis and drafts the plan. The clinician reviews and approves every recommendation before it informs care.

“Genetic data becomes far more powerful when it is connected to the rest of the patient’s health,” said Dr. Puya Yazdi, PromicsEdge’s Chief Medical Officer. “By bringing PromicsEdge’s genomic intelligence into Longevity AI, practitioners can move from understanding predisposition to delivering care that reflects the whole individual.”

The PromicsEdge integration is available now for clinics and health systems using Longevity AI.

This is truly personalized medicine.

Book a demo to see the PromicsEdge integration in action.