Decoding Energy Expenditure in Colorectal Cancer Patients: Insights from the PRIMe Study
Ever wondered how energy expenditure relates to cancer? A recent study has delved into this question, focusing on patients with colorectal cancer. The study used a method called whole-room indirect calorimetry, which measures the total energy expenditure (TEE) - the total amount of calories a person burns in a day. The study aimed to understand TEE, its predictors, and how it compares to predicted energy requirements specific to cancer patients.
The study included patients with stage II-IV colorectal cancer and found that TEE was higher in males, patients with colon cancer, and those with obesity. Interestingly, the amount of lean tissue in the limbs and the location of the tumor were independent predictors of TEE. However, the predicted energy requirements using a common formula (30 kcal/kg) overestimated TEE, especially in obese patients. This suggests that the formula may not be accurate for all patients, and special considerations are needed when determining TEE for patients with colorectal cancer.
This study is the largest of its kind to assess TEE in cancer patients using whole-room indirect calorimetry. It underscores the need for improved methods to determine energy requirements in this population. So, the next time you hear about energy expenditure and cancer, remember, it's not just about the calories, but also about the individual's body composition and tumor location.